021-51111890/在线客服
购物车（）
sales@molnova.cn
  • 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
    963389683
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号
首页- Products - Apoptosis - Apoptosis - Sodium Oxamate

Sodium Oxamate

CAS No. 565-73-1

Sodium Oxamate ( SO, oxamate sodium, Aminooxoacetic acid sodium salt, Oxamic acid sodium salt )

产品货号. M22595 CAS No. 565-73-1

Sodium Oxamate is an LDH inhibitor.?Sodium oxamate (SO) induces G2/M cell cycle arrest via downregulation of the CDK1/cyclin B1 pathway and promotes apoptosis through enhancement of mitochondrial ROS generation.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
1G ￥259 有现货
拼团 产品询价 大包装询价 加入购物车

生物学信息

  • 产品名称
    Sodium Oxamate
  • 注意事项
    本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
  • 产品简述
    Sodium Oxamate is an LDH inhibitor.?Sodium oxamate (SO) induces G2/M cell cycle arrest via downregulation of the CDK1/cyclin B1 pathway and promotes apoptosis through enhancement of mitochondrial ROS generation.
  • 产品描述
    Sodium Oxamate is an LDH inhibitor.?Sodium oxamate (SO) induces G2/M cell cycle arrest via downregulation of the CDK1/cyclin B1 pathway and promotes apoptosis through enhancement of mitochondrial ROS generation.It inhibits L(+)-lactate dehydrogenase and derails the entire gluconeogenic pathway.NETosis and lactate accumulation during LPS induced sepsis in mice was inhibited by sodium oxamate, LDH inhibitor.
  • 同义词
    SO, oxamate sodium, Aminooxoacetic acid sodium salt, Oxamic acid sodium salt
  • 通路
    Apoptosis
  • 靶点
    Apoptosis
  • 受体
    LDH;CDK;Apoptosis
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    565-73-1
  • 分子量
    111.03
  • 分子式
    C2H2NNaO3
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    [Na+].NC(=O)C([O-])=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Awasthi D , Nagarkoti S , Sadaf S , et al. Glycolysis dependent lactate formation in neutrophils: A metabolic link between NOX-dependent and independent NETosis[J]. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2019, 1865(12):165542-.
计算器

浓度计算器

摩尔计算器

分子量计算器

产品手册
关联产品

  • 9-dihydro-13-acetylb...

    9-Dihydro-13-acetylbaccatin III is an apoptosis inducer. It shows cytotoxicity against the MCF7 cell line and drug-resistant cell line MCF7-ADR.

  • Pipobroman

    Pipobroman is an anti-cancer drug that probably acts as an alkylating agent.

  • NSC 146109 hydrochlo...

    NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.

登录 注册